Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.65 |
| ▸ | DRD3 | P35462 | 11/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315747 | 1.00 | DRD2 (0.65) | DRD2DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL8315745 | 1.00 | DRD2 (0.65) | DRD2DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL2003487 | 0.87 | DRD2 (0.67) | DRD2DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL8006670 | 0.87 | DRD2 (0.67) | DRD2DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL12197603 | 0.87 | DRD2 (0.67) | DRD2DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL8314148 | 0.85 | DRD2 (0.60) | DRD2DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL350298 | 0.85 | DRD2 (0.60) | DRD2DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL8314144 | 0.85 | DRD2 (0.60) | DRD2DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL29960543 | 0.85 | DRD2 (0.60) | DRD2DRD3CHRM2HTR1AADRA2A | |
| SCHEMBL24672049 | 0.81 | FUCA1 (0.51) | DRD2DRD3DPP4ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691342-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-04-28 | — | — | EP | disclosed |
| US-5723484-A | Benzopyran compounds as 5-HT2C receptor antagonists | ADIR ET COMPAGNIE (FR) | 1998-03-03 | — | — | US | disclosed |
| US-5663191-A | PSYCHIATRIC DISEASES, ANXIETY AND ANTIDEPRESSANTS | ADIR ET COMPAGNIE (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0691342-A1 | Benzopyrane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |