Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314144 | 0.86 | DRD2 (0.60) | FUCA1DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL29960543 | 0.86 | DRD2 (0.60) | FUCA1DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL350298 | 0.86 | DRD2 (0.60) | FUCA1DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8314148 | 0.86 | DRD2 (0.60) | FUCA1DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8318673 | 0.82 | DPP4 (0.49) | FUCA1DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8318677 | 0.82 | DPP4 (0.49) | FUCA1DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8318672 | 0.82 | DPP4 (0.49) | FUCA1DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8315743 | 0.81 | DRD2 (0.65) | DRD2DRD3SIGMAR1ALDH1A1DPP4 | |
| SCHEMBL8315747 | 0.81 | DRD2 (0.65) | DRD2DRD3SIGMAR1ALDH1A1DPP4 | |
| SCHEMBL8315745 | 0.81 | DRD2 (0.65) | DRD2DRD3SIGMAR1ALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |