Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944480 | 0.85 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL8560154 | 0.82 | MEN1 (0.51) | MEN1ALDH1A1MAPTALOX15HTT | |
| SCHEMBL8314472 | 0.80 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL8312897 | 0.78 | AVPR2 (0.54) | AVPR2AVPR1A | |
| SCHEMBL5738340 | 0.76 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL7332351 | 0.76 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL8316867 | 0.76 | AVPR2 (0.52) | AVPR2AVPR1A | |
| SCHEMBL8312692 | 0.76 | AVPR2 (0.47) | AVPR2AVPR1A | |
| SCHEMBL6624184 | 0.75 | AVPR1A (0.51) | KMT2AAVPR2AVPR1A | |
| SCHEMBL7329926 | 0.75 | AVPR1A (0.52) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |