Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559415 | 0.90 | AVPR2 (0.49) | MEN1ALDH1A1MAPTALOX15HTT | |
| SCHEMBL8944480 | 0.84 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL8315883 | 0.82 | MEN1 (0.45) | MEN1ALDH1A1MAPTALOX15HTT | |
| SCHEMBL8560873 | 0.77 | ACHE (0.60) | NAMPTAVPR2AVPR1A | |
| SCHEMBL8565959 | 0.75 | AVPR2 (0.50) | ALDH1A1AVPR2AVPR1A | |
| SCHEMBL8558993 | 0.74 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8556851 | 0.74 | AVPR2 (0.58) | MEN1KMT2AAVPR2AVPR1A | |
| SCHEMBL8560660 | 0.73 | NPC1 (0.54) | NAMPTAVPR2AVPR1A | |
| SCHEMBL7369344 | 0.73 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL8563073 | 0.72 | AVPR1A (0.51) | NAMPTAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |