Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316109 | 1.00 | S1PR5 (0.46) | S1PR5S1PR1DRD2DRD3PRKX | |
| SCHEMBL8686321 | 0.91 | DRD2 (0.43) | S1PR5S1PR1DRD2DRD3RORC | |
| SCHEMBL8686324 | 0.91 | DRD2 (0.43) | S1PR5S1PR1DRD2DRD3RORC | |
| SCHEMBL8317313 | 0.89 | SLC6A12 (0.50) | S1PR5S1PR1DRD2DRD3SIGMAR1 | |
| SCHEMBL8317312 | 0.89 | SLC6A12 (0.50) | S1PR5S1PR1DRD2DRD3SIGMAR1 | |
| SCHEMBL1896734 | 0.84 | S1PR5 (0.50) | S1PR5S1PR1DRD2DRD3PRKX | |
| SCHEMBL8447023 | 0.84 | DRD4 (0.45) | S1PR5S1PR1DRD2DRD3RORC | |
| SCHEMBL8447022 | 0.84 | DRD4 (0.45) | S1PR5S1PR1DRD2DRD3RORC | |
| SCHEMBL8782076 | 0.83 | MEN1 (0.54) | S1PR5S1PR1DRD2DRD3RORC | |
| SCHEMBL8782084 | 0.83 | MEN1 (0.54) | S1PR5S1PR1DRD2DRD3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691342-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-04-28 | — | — | EP | disclosed |
| EP-0691342-A1 | Benzopyrane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |