Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310631 | 0.88 | F2RL3 (0.35) | F2RL3MEN1KMT2ASLC26A4HTT | |
| SCHEMBL8310753 | 0.87 | ALDH1A1 (0.45) | F2RL3MEN1KMT2ASLC26A4HTT | |
| SCHEMBL8314208 | 0.84 | F2RL3 (0.36) | F2RL3MEN1KMT2ASLC26A4HTT | |
| SCHEMBL8315191 | 0.83 | MAPK1 (0.41) | F2RL3MEN1KMT2ANPSR1CYP19A1 | |
| SCHEMBL8316352 | 0.83 | F2RL3 (0.33) | F2RL3MEN1KMT2AALDH1A1 | |
| SCHEMBL8310437 | 0.83 | F2RL3 (0.35) | F2RL3MEN1KMT2ASLC26A4HTT | |
| SCHEMBL8311214 | 0.82 | S1PR1 (0.39) | F2RL3MEN1KMT2ASLC26A4MAPT | |
| SCHEMBL8314569 | 0.82 | AR (0.36) | F2RL3MEN1KMT2ASLC26A4HTT | |
| SCHEMBL8312516 | 0.82 | MAPT (0.49) | MEN1KMT2AHTTCYP19A1MAPT | |
| SCHEMBL8315476 | 0.82 | CYP19A1 (0.43) | F2RL3MEN1KMT2AHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |