Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 5/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 2/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8318882 | 0.99 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ABRD4AR | |
| SCHEMBL8319665 | 0.92 | BRD4 (0.46) | ALDH1A1MEN1KMT2ABRD4AR | |
| SCHEMBL8317477 | 0.92 | BRD4 (0.46) | ALDH1A1MEN1KMT2ABRD4AR | |
| SCHEMBL8316419 | 0.88 | BRD4 (0.42) | ALDH1A1MEN1KMT2ABRD4AR | |
| SCHEMBL8316577 | 0.87 | CCKBR (0.44) | ALDH1A1MEN1KMT2ABRD4BRD2 | |
| SCHEMBL8317415 | 0.86 | BRD4 (0.50) | ALDH1A1BRD4BRD2BRD3POLB | |
| SCHEMBL8316853 | 0.86 | BRD4 (0.50) | ALDH1A1BRD4BRD2BRD3POLB | |
| SCHEMBL8316544 | 0.86 | AR (0.42) | ALDH1A1MEN1KMT2ABRD4AR | |
| Hydrochloric Acid SCHEMBL8319758 | 0.85 | BRD4 (0.49) | ALDH1A1BRD4BRD2BRD3POLB | |
| SCHEMBL8316425 | 0.84 | BRD4 (0.46) | ALDH1A1BRD4BRD2BRD3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | claimed |
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |