Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1440000 | 0.90 | MAPT (0.55) | HRH3KCNH2MAPTKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL20139479 | 0.89 | MAPT (0.54) | HRH3KCNH2MAPTKDM4EKMT2A | |
| SCHEMBL6950591 | 0.87 | MAPT (0.55) | HRH3KCNH2MAPTKDM4ELMNA | |
| SCHEMBL15569388 | 0.87 | MAPT (0.62) | KCNH2MAPTKDM4ELMNALTA4H | |
| SCHEMBL6973109 | 0.84 | KCNH2 (0.55) | HRH3KCNH2MAPTKDM4ELMNA | |
| SCHEMBL22301206 | 0.84 | KCNH2 (0.55) | HRH3KCNH2MAPTKDM4ELMNA | |
| SCHEMBL11454925 | 0.84 | LMNA (0.54) | HRH3KCNH2MAPTKMT2ALMNA | |
| SCHEMBL30414662 | 0.84 | MAPT (0.55) | KCNH2MAPTKDM4ELMNALTA4H | |
| SCHEMBL4172495 | 0.83 | MAPT (0.58) | KCNH2MAPTKDM4ELMNALTA4H | |
| Hydrochloric Acid SCHEMBL6751953 | 0.83 | KCNH2 (0.55) | HRH3KCNH2MAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |