Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587545 | 0.95 | POLB (0.70) | POLBKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL4120652 | 0.93 | POLB (0.58) | POLBKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL2475467 | 0.88 | POLB (0.52) | POLBKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL8320550 | 0.83 | KMT2A (0.81) | POLBKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL8589037 | 0.83 | KMT2A (0.69) | POLBKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL4609736 | 0.83 | POLB (0.70) | POLBKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL23291774 | 0.81 | POLB (0.63) | POLBKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL2535206 | 0.81 | POLB (0.63) | POLBKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL27965851 | 0.81 | POLB (0.63) | POLBKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL4805229 | 0.80 | KMT2A (0.75) | POLBKMT2AHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161962-A | Sulphonic-acid-amide derivative | KONO PHARMACEUTICAL IND K K (JP) | 1997-10-15 | — | — | CN | claimed |
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |
| CN-1161962-A | Sulphonic-acid-amide derivative | KONO PHARMACEUTICAL IND K K (JP) | 1997-10-15 | — | — | CN | disclosed |