Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1988984 | 0.90 | EPHX2 (0.48) | SMN1; SMN2HTTMMP12TSHRFOLH1 | |
| SCHEMBL7708032 | 0.89 | TSHR (0.56) | SMN1; SMN2HTTTSHRFOLH1LMNA | |
| SCHEMBL27795888 | 0.87 | EPHX2 (0.46) | SMN1; SMN2HTTMMP12TSHRFOLH1 | |
| SCHEMBL9152709 | 0.86 | ALDH1A1 (0.49) | SMN1; SMN2HTTTSHRFOLH1LMNA | |
| SCHEMBL508419 | 0.85 | TSHR (0.56) | SMN1; SMN2HTTMMP12TSHRFOLH1 | |
| SCHEMBL6508631 | 0.85 | ALDH1A1 (0.49) | SMN1; SMN2HTTTSHRFOLH1LMNA | |
| SCHEMBL19987762 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTTSHRFOLH1LMNA | |
| SCHEMBL28739368 | 0.84 | ALDH1A1 (0.52) | SMN1; SMN2HTTTSHRLMNAALDH1A1 | |
| SCHEMBL15862001 | 0.84 | NPC1 (0.50) | SMN1; SMN2HTTTSHRFOLH1LMNA | |
| SCHEMBL14949713 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2HTTTSHRFOLH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736225-A | Continuous preparation method of dorterevir | 华东理工大学 | 2024-03-22 | — | — | CN | claimed |
| CN-117736225-A | Continuous preparation method of dorterevir | 华东理工大学 | 2024-03-22 | — | — | CN | disclosed |
| EP-0484881-B1 | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics | SQUIBB & SONS INC (US) | 1999-04-07 | — | — | EP | disclosed |
| US-5705645-A | Hereroaryl derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5420277-A | BACTERICIDE INTERMEDIATES | E. R. SQUIBB & SONS, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0484881-A2 | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1992-05-13 | — | — | EP | disclosed |