Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.67 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316875 | 1.00 | DRD2 (0.67) | DRD2DRD3SIGMAR1HTR1AHTR7 | |
| SCHEMBL8316870 | 1.00 | DRD2 (0.67) | DRD2DRD3SIGMAR1HTR1AHTR7 | |
| SCHEMBL8314148 | 0.81 | DRD2 (0.60) | DRD2DRD3HTR1AHTR6HTR2A | |
| SCHEMBL350298 | 0.81 | DRD2 (0.60) | DRD2DRD3HTR1AHTR6HTR2A | |
| SCHEMBL29960543 | 0.81 | DRD2 (0.60) | DRD2DRD3HTR1AHTR6HTR2A | |
| SCHEMBL8314144 | 0.81 | DRD2 (0.60) | DRD2DRD3HTR1AHTR6HTR2A | |
| SCHEMBL8315986 | 0.81 | DRD2 (1.00) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL8314639 | 0.81 | DRD2 (1.00) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8686327 | 0.80 | DRD2 (0.98) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8686468 | 0.80 | DRD2 (0.98) | DRD2DRD3SIGMAR1HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691342-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-04-28 | — | — | EP | disclosed |
| US-5663191-A | PSYCHIATRIC DISEASES, ANXIETY AND ANTIDEPRESSANTS | ADIR ET COMPAGNIE (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0691342-A1 | Benzopyrane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |