Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12571335 | 0.80 | MAPK10 (0.41) | MAPK10TDP1DGAT1CA1CA2 | |
| SCHEMBL15096829 | 0.80 | MAPK10 (0.41) | MAPK10TDP1DGAT1CA1CA2 | |
| SCHEMBL5729371 | 0.78 | CTSK (0.42) | MAPK10TDP1DGAT1CA1CA2 | |
| SCHEMBL208785 | 0.78 | CTSK (0.42) | MAPK10TDP1DGAT1CA1CA2 | |
| SCHEMBL6595757 | 0.76 | MAPK10 (0.39) | MAPK10TDP1DGAT1CA1CA2 | |
| SCHEMBL27733205 | 0.76 | MAPK10 (0.39) | MAPK10TDP1DGAT1CA1CA2 | |
| SCHEMBL1140993 | 0.76 | MAPK10 (0.39) | MAPK10TDP1DGAT1CA1CA2 | |
| SCHEMBL4774889 | 0.76 | MAPK10 (0.42) | MAPK10TDP1DGAT1CA1CA2 | |
| SCHEMBL16938665 | 0.74 | MAPK10 (0.38) | MAPK10TDP1DGAT1CA1CA2 | |
| SCHEMBL166623 | 0.74 | CA1 (0.42) | MAPK10TDP1DGAT1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938474-A2 | CYCLOPROPYLINDOLE COMPOUNDS AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998011101-A2 | CONDENSED N-ACLYINDOLES AS ANTITUMOR AGENTS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |