Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355446 | 0.86 | HTT (0.46) | HTTCYP3A4ALDH1A1MAPK1HPGD | |
| SCHEMBL2188777 | 0.85 | ALDH1A1 (0.44) | HTTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL2443988 | 0.83 | GAA (0.45) | HTTALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL2551636 | 0.83 | PARP10 (0.41) | HTTCYP3A4ALDH1A1HPGDLMNA | |
| SCHEMBL2554120 | 0.80 | PLK1 (0.49) | HTTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL2552993 | 0.80 | MAPT (0.37) | HTTCYP3A4ALDH1A1HPGDLMNA | |
| SCHEMBL3516973 | 0.78 | LMNA (0.45) | HTTALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2900063 | 0.78 | GAA (0.49) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL27833658 | 0.78 | MAPT (0.36) | HTTALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL1809516 | 0.78 | TSHR (0.49) | ALDH1A1HPGDLMNAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721482-B | Light absorber and organic electroluminescent device including the same | 三星显示有限公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5807850-A | Therapeutic agent for osteoporosis and triazepine compound | JAPAN TOBACCO, INC. (JP) | 1998-09-15 | — | — | US | disclosed |
| CN-1171788-A | Therapeutic agent for osteoporosis and triaza * compound | JAPAN TOBACCO INC (JP) | 1998-01-28 | — | — | CN | disclosed |
| EP-0792880-A1 | OSTEOPOROSIS REMEDY AND TRIAZEPINE COMPOUND | Japan Tobacco Inc. (JP) | 1997-09-03 | — | — | EP | disclosed |