Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloheptane SCHEMBL8315045 | 1.00 | HTR1A (0.50) | HTR1AHTR1DNFKB1NFKB2RELA | |
| SCHEMBL7313786 | 0.88 | KMT2A (0.50) | HTR1AHTR1DNFKB1NFKB2RELA | |
| SCHEMBL7321928 | 0.88 | KMT2A (0.50) | HTR1AHTR1DNFKB1NFKB2RELA | |
| SCHEMBL7317381 | 0.82 | HTR1A (0.56) | HTR1AHTR1DNFKB1NFKB2RELA | |
| SCHEMBL7307892 | 0.82 | HTR1A (0.56) | HTR1AHTR1DNFKB1NFKB2RELA | |
| SCHEMBL7321215 | 0.82 | HTR1A (0.56) | HTR1AHTR1DNFKB1NFKB2RELA | |
| SCHEMBL7318030 | 0.82 | HTR1A (0.56) | HTR1AHTR1DNFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL467043 | 0.81 | HTR1A (0.55) | HTR1AHTR1DNFKB1NFKB2RELA | |
| SCHEMBL7114723 | 0.79 | KDM4E (0.48) | HTR1AHTR1DMTNR1AMTNR1BHPGD | |
| SCHEMBL6626738 | 0.79 | KDM4E (0.48) | HTR1AHTR1DMTNR1AMTNR1BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540914-B1 | 2-Aminomethylchromans as active ingredients in medicaments for the treatment of diseases of the central nervous system | BAYER AG (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0540914-A1 | 2-Aminomethylchromans as active ingredients in medicaments for the treatment of diseases of the central nervous system | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |