Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 4/20 | 0.52 |
| ▸ | BACE1 | P56817 | 4/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317320 | 0.91 | GSK3B (0.58) | MMP1GSK3BBACE1MAOBNPC1 | |
| SCHEMBL8317285 | 0.89 | GSK3B (0.55) | MMP1GSK3BBACE1MAOBNR1H4 | |
| SCHEMBL8317781 | 0.89 | GSK3B (0.57) | MMP1GSK3BBACE1MAOBNPC1 | |
| SCHEMBL6539315 | 0.86 | GSK3B (0.68) | GSK3BBACE1MAOBNR1H4EGFR | |
| SCHEMBL6539306 | 0.86 | GSK3B (0.68) | GSK3BBACE1MAOBNR1H4EGFR | |
| SCHEMBL8320471 | 0.84 | GSK3B (0.52) | MMP1GSK3BBACE1MAOBNPC1 | |
| SCHEMBL231089 | 0.78 | LMNA (0.56) | NR1H4LMNAL3MBTL1 | |
| SCHEMBL14021580 | 0.78 | NR1H4 (0.60) | GSK3BBACE1MAOBNR1H4NPC1 | |
| SCHEMBL15687587 | 0.78 | LMNA (0.77) | GSK3BBACE1MAOBNPC1RAB9A | |
| SCHEMBL15687588 | 0.78 | LMNA (0.77) | GSK3BBACE1MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |