Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.55 |
| ▸ | BACE1 | P56817 | 4/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539306 | 0.89 | GSK3B (0.68) | GSK3BBACE1NR1H4NPC1RAB9A | |
| SCHEMBL6539315 | 0.89 | GSK3B (0.68) | GSK3BBACE1NR1H4NPC1RAB9A | |
| SCHEMBL8317289 | 0.89 | MMP1 (0.55) | GSK3BBACE1NR1H4MMP1NPC1 | |
| SCHEMBL8320370 | 0.84 | GSK3B (0.62) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14021580 | 0.81 | NR1H4 (0.60) | GSK3BBACE1NR1H4NPC1RAB9A | |
| SCHEMBL13678668 | 0.81 | ALDH1A1 (0.55) | GSK3BBACE1NR1H4EGFRERBB2 | |
| SCHEMBL15687587 | 0.80 | LMNA (0.77) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15687588 | 0.80 | LMNA (0.77) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13791103 | 0.80 | KDM4E (0.56) | GSK3BBACE1NR1H4MAOBCA12 | |
| SCHEMBL8322091 | 0.79 | RAB9A (0.55) | GSK3BBACE1RAB9AMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |