Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.49 |
| ▸ | CDK9 | P50750 | 2/20 | 0.49 |
| ▸ | PRKACA | P17612 | 9/20 | 0.47 |
| ▸ | PRKACG | P22612 | 9/20 | 0.47 |
| ▸ | PRKACB | P22694 | 9/20 | 0.47 |
| ▸ | CDK4 | P11802 | 3/20 | 0.47 |
| ▸ | CCND1 | P24385 | 3/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313886 | 0.89 | PRKACA (0.61) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL9057654 | 0.82 | RPS6KB1 (0.72) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL8314260 | 0.73 | SIRT2 (0.69) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL8319736 | 0.72 | CDK4 (0.47) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL9374625 | 0.72 | RPS6KB1 (0.77) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL28101293 | 0.71 | SIRT2 (0.60) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL9375258 | 0.71 | SIRT2 (0.49) | SIRT2MEN1TP53MAPTMAPK1 | |
| SCHEMBL8316997 | 0.71 | SIRT2 (0.53) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL28101300 | 0.70 | SIRT2 (0.58) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL28655141 | 0.69 | PRKACA (0.61) | RPS6KB1CCNT1CDK9PRKACAPRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | disclosed |
| US-5547976-A | VIRICIDES, HERPES VIRUS, CYTOMEGALOVIRUS; CARDIOVASCULAR DISORDERS | BURROUGHS WELLCOME CO. (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0630242-A1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| EP-0630241-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018766-A1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |
| WO-1993018765-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |