Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.72 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.61 |
| ▸ | CDK9 | P50750 | 2/20 | 0.61 |
| ▸ | PRKACA | P17612 | 10/20 | 0.59 |
| ▸ | PRKACG | P22612 | 10/20 | 0.59 |
| ▸ | PRKACB | P22694 | 10/20 | 0.59 |
| ▸ | CDK4 | P11802 | 4/20 | 0.59 |
| ▸ | CCND1 | P24385 | 4/20 | 0.59 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.56 |
| ▸ | CDK1 | P06493 | 3/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374625 | 0.88 | RPS6KB1 (0.77) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL8317356 | 0.82 | RPS6KB1 (0.50) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL7199461 | 0.82 | PRKACA (0.81) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL28101193 | 0.80 | RPS6KB1 (0.74) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL14041797 | 0.77 | PRKD1 (0.67) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL7195523 | 0.77 | CCNT1 (0.81) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL8162860 | 0.76 | CCNT1 (0.53) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL3945882 | 0.75 | SIRT2 (1.00) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL30958473 | 0.75 | SIRT2 (1.00) | RPS6KB1CCNT1CDK9PRKACAPRKACG | |
| SCHEMBL9376063 | 0.74 | PRKACA (0.68) | RPS6KB1CCNT1CDK9PRKACAPRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018765-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | claimed |
| WO-1996004906-A1 | COMPOUNDS FOR THE TREATMENT OF RESTENOSIS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |
| WO-1993018765-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |