Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3529341 | 0.81 | SLC6A3 (0.43) | SLC6A3SLC6A4ALDH1A1MEN1HPGD | |
| SCHEMBL558007 | 0.76 | SLC6A3 (0.97) | SLC6A3SLC6A4LMNA | |
| SCHEMBL3443527 | 0.76 | SLC6A3 (0.49) | SLC6A3SLC6A4LMNAACHEMAPT | |
| Tert-Butyl Formate SCHEMBL27621365 | 0.75 | SLC6A3 (0.39) | SLC6A3SLC6A4LMNAMAPTKDM4E | |
| SCHEMBL3517809 | 0.75 | SLC6A3 (1.00) | SLC6A3SLC6A4LMNA | |
| SCHEMBL27621361 | 0.75 | SLC6A3 (0.40) | SLC6A3SLC6A4LMNAKDM4EALDH1A1 | |
| SCHEMBL3525838 | 0.75 | GPR183 (0.54) | — | |
| SCHEMBL11103974 | 0.73 | SLC6A4 (0.63) | SLC6A3SLC6A4 | |
| SCHEMBL8804864 | 0.73 | SLC6A3 (0.97) | SLC6A3SLC6A4LMNA | |
| SCHEMBL6352266 | 0.72 | SLC6A3 (0.47) | SLC6A3SLC6A4LMNAACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |