Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 11/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320373 | 0.90 | HDAC1 (0.57) | HDAC3HDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL8314608 | 0.88 | ALDH1A1 (0.55) | HDAC3HDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL4264043 | 0.84 | HDAC3 (0.78) | HDAC3HDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL4264038 | 0.84 | HDAC3 (0.78) | HDAC3HDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL3293881 | 0.80 | HDAC2 (0.71) | HDAC3HDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL3293874 | 0.80 | HDAC2 (0.71) | HDAC3HDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL8313475 | 0.77 | ALDH1A1 (0.48) | HDAC3HDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL15087664 | 0.73 | CNR2 (0.74) | HDAC3HDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL8317483 | 0.73 | ALDH1A1 (0.52) | HDAC3HDAC6HDAC1HDAC8HDAC2 | |
| SCHEMBL17200222 | 0.72 | SMN1; SMN2 (0.66) | HDAC3HDAC6HDAC1HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |