Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320373 | 0.89 | HDAC1 (0.57) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8314608 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8317458 | 0.88 | PKM (0.49) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8322075 | 0.86 | RXRA (0.46) | ALDH1A1MAPTKMT2AMEN1HDAC3 | |
| SCHEMBL8317483 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8314172 | 0.85 | LMNA (0.47) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8317750 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8317387 | 0.79 | ALOX5 (0.50) | ALDH1A1MAPTKMT2AHDAC1NPSR1 | |
| SCHEMBL8317433 | 0.77 | HDAC3 (0.58) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL8053440 | 0.74 | NPSR1 (0.57) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |