Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318310 | 0.90 | AVPR1A (0.54) | AVPR2AVPR1AMAPTALDH1A1RAB9A | |
| SCHEMBL7418830 | 0.90 | ALDH1A1 (0.53) | MAPTALDH1A1RAB9AACHE | |
| SCHEMBL8317969 | 0.90 | MAPT (0.49) | AVPR2AVPR1AMAPTALDH1A1RAB9A | |
| SCHEMBL8316224 | 0.88 | AVPR2 (0.44) | AVPR2AVPR1AOXTR | |
| SCHEMBL8315722 | 0.87 | AVPR1A (0.64) | AVPR2AVPR1AOXTR | |
| SCHEMBL8314568 | 0.85 | AVPR1A (0.58) | AVPR2AVPR1A | |
| SCHEMBL8312611 | 0.85 | AVPR1A (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL8314000 | 0.85 | AVPR1A (0.56) | AVPR2AVPR1AOXTR | |
| SCHEMBL8319346 | 0.84 | AVPR1A (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL8318558 | 0.83 | AVPR1A (0.48) | AVPR2AVPR1AMAPTALDH1A1OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |