Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317555 | 0.90 | AVPR2 (0.54) | AVPR1AMAPTGFERRAB9AAVPR2 | |
| SCHEMBL7412836 | 0.90 | AVPR1A (0.51) | AVPR1AGAARAB9AAVPR2 | |
| SCHEMBL8315401 | 0.87 | AVPR1A (0.51) | AVPR1AAVPR2 | |
| SCHEMBL8314325 | 0.85 | AVPR1A (0.52) | AVPR1AKMT2AAVPR2 | |
| SCHEMBL8317969 | 0.84 | MAPT (0.49) | AVPR1AMAPTKMT2ARAB9AAVPR2 | |
| SCHEMBL8317310 | 0.82 | AVPR1A (0.52) | AVPR1AGAAMAPTGFERKMT2A | |
| SCHEMBL8315722 | 0.81 | AVPR1A (0.64) | AVPR1AAVPR2 | |
| SCHEMBL8314000 | 0.81 | AVPR1A (0.56) | AVPR1AAVPR2 | |
| SCHEMBL8557218 | 0.80 | AVPR1A (0.60) | AVPR1AGAAMAPTGFERRAB9A | |
| SCHEMBL7418830 | 0.80 | ALDH1A1 (0.53) | MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |