Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317310 | 0.91 | AVPR1A (0.52) | AVPR2AVPR1AMAPTALDH1A1RAB9A | |
| SCHEMBL8318571 | 0.91 | MAPT (0.47) | AVPR2AVPR1AMAPTALDH1A1RAB9A | |
| SCHEMBL8318313 | 0.90 | AVPR2 (0.45) | AVPR2AVPR1AMAPT | |
| SCHEMBL8316236 | 0.89 | AVPR2 (0.42) | AVPR2AVPR1AOXTR | |
| SCHEMBL7333364 | 0.88 | AVPR1A (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL8315532 | 0.86 | AVPR1A (0.55) | AVPR2AVPR1AOXTR | |
| SCHEMBL8311577 | 0.85 | AVPR1A (0.51) | AVPR2AVPR1AOXTR | |
| SCHEMBL8318225 | 0.85 | AVPR1A (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL8316223 | 0.85 | GAA (0.46) | MAPTALDH1A1GFERSMN1; SMN2 | |
| SCHEMBL8317072 | 0.85 | AVPR1A (0.50) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |