Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317702 | 0.91 | AVPR2 (0.52) | AVPR1ARAB9AMAPTGFERAVPR2 | |
| SCHEMBL8314230 | 0.88 | AVPR1A (0.48) | AVPR1AAVPR2 | |
| SCHEMBL8317401 | 0.86 | AVPR1A (0.50) | AVPR1AKMT2AAVPR2 | |
| SCHEMBL8318571 | 0.85 | MAPT (0.47) | AVPR1ARAB9AMAPTKMT2AAVPR2 | |
| SCHEMBL8316223 | 0.85 | GAA (0.46) | GAAMAPTGFERKMT2AALDH1A1 | |
| SCHEMBL8318313 | 0.85 | AVPR2 (0.45) | AVPR1AMAPTAVPR2 | |
| SCHEMBL8318310 | 0.82 | AVPR1A (0.54) | AVPR1AGAARAB9AMAPTGFER | |
| SCHEMBL7333364 | 0.82 | AVPR1A (0.61) | AVPR1AAVPR2 | |
| SCHEMBL8318225 | 0.82 | AVPR1A (0.53) | AVPR1AAVPR2 | |
| SCHEMBL8316236 | 0.81 | AVPR2 (0.42) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |