Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.42 |
| ▸ | OXTR | P30559 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317702 | 0.89 | AVPR2 (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL8318538 | 0.87 | LMNA (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL8315532 | 0.84 | AVPR1A (0.55) | AVPR2AVPR1AOXTR | |
| SCHEMBL7333364 | 0.84 | AVPR1A (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL8316224 | 0.83 | AVPR2 (0.44) | AVPR2AVPR1AOXTR | |
| SCHEMBL8314084 | 0.83 | AVPR1A (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL8317310 | 0.81 | AVPR1A (0.52) | AVPR2AVPR1A | |
| SCHEMBL8318225 | 0.81 | AVPR1A (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL8317384 | 0.81 | AVPR1A (0.49) | AVPR2AVPR1AOXTR | |
| SCHEMBL8318571 | 0.81 | MAPT (0.47) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |