Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27010079 | 0.86 | TAAR1 (0.38) | AOC3DRD2DRD3TDP1TAAR1 | |
| SCHEMBL26122242 | 0.74 | CYP19A1 (0.35) | CYP3A4TSHRPIK3CATDP1ALDH1A1 | |
| SCHEMBL8313252 | 0.70 | TDP1 (0.43) | TSHRTDP1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL24316013 | 0.68 | TAAR1 (0.34) | AOC3DRD2DRD3TDP1TAAR1 | |
| SCHEMBL30936694 | 0.67 | BRD4 (0.36) | TDP1 | |
| SCHEMBL30936652 | 0.67 | PABPC1 (0.37) | CYP3A4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9607569 | 0.67 | CYP3A4 (0.39) | CYP3A4TSHRPIK3CATDP1CD44 | |
| SCHEMBL27010080 | 0.67 | TAAR1 (0.41) | AOC3TDP1TAAR1ALDH1A1HPGD | |
| SCHEMBL23278085 | 0.67 | CHEK1 (0.42) | AOC3CYP3A4TSHRPIK3CATDP1 | |
| SCHEMBL7697624 | 0.67 | KCNH2 (0.42) | AOC3TSHRTDP1TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929072-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |
| WO-1999010346-A1 | BENZOTHIADIAZINYL-INDOLE DERIVATIVES AND THEIR USE AS SEROTONIN RECEPTOR LIGANDS | ELI LILLY AND COMPANY LIMITED (GB) | 1999-03-04 | — | — | WO | disclosed |
| EP-0897921-A1 | Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands | ELI LILLY AND COMPANY LIMITED (GB) | 1999-02-24 | — | — | EP | disclosed |