Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316276 | 0.74 | SMN1; SMN2 (0.49) | RAB9AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6571403 | 0.73 | NPC1 (0.59) | RAB9AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13834567 | 0.73 | RAB9A (0.72) | RAB9AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13834568 | 0.73 | RAB9A (0.72) | RAB9AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6571399 | 0.73 | NPC1 (0.59) | RAB9AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14400125 | 0.71 | ABL1 (0.48) | RAB9AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14399704 | 0.71 | ABL1 (0.44) | KDM4EALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL29963430 | 0.70 | MAPT (0.71) | RAB9AKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL332626 | 0.70 | MAPT (0.71) | RAB9AKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9419873 | 0.70 | MAPT (0.52) | RAB9AKDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |
| EP-0792880-A1 | OSTEOPOROSIS REMEDY AND TRIAZEPINE COMPOUND | Japan Tobacco Inc. (JP) | 1997-09-03 | — | — | EP | disclosed |