SCHEMBL8318315

SCHEMBL8318315

Clc1ccc2c(c1)[C@H]1CN(Cc3ccccc3)C[C@@H]1CO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 17/20 1.00
DRD3 P35462 17/20 1.00
DPP4 P27487 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8313033 1.00 DRD2 (1.00) DRD2DRD3DPP4
Hydrochloric Acid SCHEMBL8686313 0.99 DRD2 (0.97) DRD2DRD3DPP4
Hydrochloric Acid SCHEMBL8685090 0.99 DRD2 (0.97) DRD2DRD3DPP4
Hydrochloric Acid SCHEMBL8902652 0.99 DRD2 (0.97) DRD2DRD3DPP4
SCHEMBL8318539 0.90 DRD2 (0.81) DRD2DRD3DPP4
Hydrochloric Acid SCHEMBL8685262 0.89 DRD2 (0.80) DRD2DRD3DPP4
Hydrochloric Acid SCHEMBL8903147 0.89 DRD2 (0.80) DRD2DRD3DPP4
SCHEMBL8317793 0.86 DRD2 (1.00) DRD2DRD3
SCHEMBL29960315 0.85 DRD2 (1.00) DRD2DRD3
SCHEMBL8317999 0.85 DRD2 (1.00) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691342-B1 Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1999-04-28 EP disclosed
EP-0691342-A1 Benzopyrane derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1996-01-10 EP disclosed