Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317211 | 0.85 | NQO2 (0.48) | NQO2KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8324287 | 0.81 | NQO2 (0.58) | NQO2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL240664 | 0.80 | NQO2 (0.57) | TLR8NQO2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9755341 | 0.79 | POLB (0.55) | TLR8NQO2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4299906 | 0.78 | ALDH1A1 (0.70) | NQO2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL15271481 | 0.78 | NQO2 (0.56) | TLR8NQO2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8418578 | 0.77 | TLR8 (0.50) | TLR8NQO2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9040694 | 0.77 | ALDH1A1 (0.60) | NQO2KDM4EALDH1A1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL32690198 | 0.77 | NQO2 (0.54) | TLR8NQO2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27751211 | 0.76 | ALDH1A1 (0.50) | NQO2KDM4EALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981541-A | ACRIDINE DERIVATIVES; ANTICANCER AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-11-09 | — | — | US | claimed |
| US-5981541-A | ACRIDINE DERIVATIVES; ANTICANCER AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0950054-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-TUMOR AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998012181-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-TUMOR AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-03-26 | — | — | WO | disclosed |