Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 9/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | WHR1 | P49842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324287 | 0.85 | NQO2 (0.58) | NQO2PDGFRBPDGFRAWHR1ALDH1A1 | |
| SCHEMBL8318316 | 0.85 | TLR8 (0.54) | NQO2PDGFRBPDGFRAALDH1A1SMN1; SMN2 | |
| SCHEMBL8320381 | 0.84 | NQO2 (0.45) | NQO2PDGFRBPDGFRASRCALDH1A1 | |
| SCHEMBL8498365 | 0.84 | TDP1 (0.44) | ALDH1A1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL27751211 | 0.80 | ALDH1A1 (0.50) | NQO2ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL8318079 | 0.79 | NQO2 (0.44) | NQO2PDGFRBPDGFRASRCWHR1 | |
| SCHEMBL9755422 | 0.78 | NQO2 (0.60) | NQO2PDGFRBPDGFRASRCALDH1A1 | |
| SCHEMBL14906876 | 0.78 | MAOA (0.38) | NQO2PDGFRBPDGFRASRCWHR1 | |
| SCHEMBL12074846 | 0.77 | NQO2 (0.40) | NQO2PDGFRBPDGFRASRCALDH1A1 | |
| SCHEMBL6616005 | 0.76 | PDPK1 (0.51) | PDGFRBPDGFRAALDH1A1SMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981541-A | ACRIDINE DERIVATIVES; ANTICANCER AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-11-09 | — | — | US | claimed |
| US-5981541-A | ACRIDINE DERIVATIVES; ANTICANCER AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0950054-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-TUMOR AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998012181-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-TUMOR AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-03-26 | — | — | WO | disclosed |