Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.68 |
| ▸ | DRD3 | P35462 | 15/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 6/20 | 0.58 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096393 | 0.86 | ADRB1 (0.59) | DRD2DRD3ADRB1DRD4 | |
| SCHEMBL3398184 | 0.82 | DRD2 (0.70) | DRD2DRD3ADRB1DRD4DRD5 | |
| SCHEMBL8452211 | 0.82 | DRD2 (0.69) | DRD2DRD3ADRB1DRD4DRD5 | |
| SCHEMBL13457329 | 0.81 | DRD2 (0.68) | DRD2DRD3ADRB1DRD4DRD5 | |
| SCHEMBL18950672 | 0.81 | DRD2 (0.68) | DRD2DRD3ADRB1DRD4DRD5 | |
| SCHEMBL3399254 | 0.81 | DRD2 (1.00) | DRD2DRD3ADRB1DRD4DRD5 | |
| SCHEMBL2096264 | 0.80 | DRD2 (0.67) | DRD2DRD3ADRB1DRD4DRD5 | |
| SCHEMBL30751119 | 0.80 | DRD2 (0.67) | DRD2DRD3ADRB1DRD4DRD5 | |
| SCHEMBL2131518 | 0.80 | DRD2 (0.67) | DRD2DRD3ADRB1DRD4DRD5 | |
| SCHEMBL14494815 | 0.78 | DRD2 (0.69) | DRD2DRD3ADRB1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |