Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201750 | 0.98 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL28590124 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4ECRHR1 | |
| SCHEMBL21843234 | 0.71 | HSP90AB1 (0.33) | ALDH1A1KDM4EGAACRHR1TSHR | |
| SCHEMBL5785398 | 0.65 | GAA (0.38) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL5789969 | 0.64 | MAPT (0.46) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL17844043 | 0.62 | RPS6KB1 (0.38) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL5826626 | 0.62 | AKT2 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL317299 | 0.61 | RAPGEF4 (0.50) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL6972495 | 0.61 | KDM4E (0.52) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL2904246 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915880-A1 | AZOLO TRIAZINES AND PYRIMIDINES | Du Pont Pharmaceuticals Company (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003510-A1 | AZOLO TRIAZINES AND PYRIMIDINES | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-01-29 | — | — | WO | disclosed |