Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SHBG | P04278 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | FOS | P01100 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317016 | 0.86 | KDM1A (0.62) | KDM4EALDH1A1KMT2ASSTR3MEN1 | |
| SCHEMBL8313921 | 0.86 | KDM1A (0.62) | KDM4EALDH1A1KMT2ASSTR3MEN1 | |
| SCHEMBL8315784 | 0.86 | KDM1A (0.62) | KDM4EALDH1A1KMT2ASSTR3MEN1 | |
| SCHEMBL139478 | 0.81 | ERCC1 (0.58) | SSTR3ALOX15 | |
| SCHEMBL8231045 | 0.81 | ERCC1 (0.58) | SSTR3ALOX15 | |
| SCHEMBL108594 | 0.81 | ERCC1 (0.58) | SSTR3ALOX15 | |
| SCHEMBL13984321 | 0.79 | ERCC1 (0.42) | TRPV1KMT2ASSTR3MEN1 | |
| SCHEMBL16463823 | 0.79 | FOS (0.49) | KDM4EALDH1A1SHBGTAAR1TSHR | |
| SCHEMBL8317756 | 0.78 | ALDH1A1 (0.81) | KDM4EALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL11969383 | 0.77 | TAAR1 (0.62) | KDM4EALDH1A1TAAR1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787716-B1 | Isoprene derivatives | NISSHIN FLOUR MILLING CO (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5756475-A | POLYISOPRENE MODIFIED WITH AMINE WITH ANTICANCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0787716-A1 | Isoprene derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |