Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 4/20 | 0.40 |
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319918 | 0.89 | GLA (0.48) | GLAGAAXDHCDK1CCNB1 | |
| SCHEMBL8320394 | 0.88 | GLA (0.45) | GLAGAAXDHCDK1CCNB1 | |
| SCHEMBL8318563 | 0.87 | GLA (0.49) | GLAGAAXDHCYP1A2NR4A2 | |
| SCHEMBL24020849 | 0.85 | IDO1 (0.46) | GLAGAAXDHCDK1CCNB1 | |
| SCHEMBL8322794 | 0.84 | KDM4E (0.57) | GLAGAAXDHCDK1CCNB1 | |
| SCHEMBL30184708 | 0.84 | XDH (0.50) | GLAGAAXDHCDK1CCNB1 | |
| SCHEMBL10093729 | 0.83 | GLA (0.46) | GLAGAAXDHCYP1A2LMNA | |
| SCHEMBL19014158 | 0.82 | IDO1 (0.49) | GLAGAAXDHCYP1A2ALPL | |
| SCHEMBL8319614 | 0.82 | GAA (0.62) | GLAGAAXDHCYP1A2LMNA | |
| SCHEMBL23049740 | 0.79 | XDH (0.44) | GLAGAAXDHCDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9048755-A | — | — | None | — | — | JP | disclosed |
| WO-2017106352-A1 | CAFFEINE INHIBITORS OF MTHFD2 AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-06-22 | — | — | WO | disclosed |
| US-5866594-A | Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0791582-A1 | INDOLE-2-CARBOXYLIC ESTER DERIVATIVES AND AGRICULTURAL AND HORTICULTURAL BACTERIOCIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-08-27 | — | — | EP | disclosed |
| JP-H0948755-A | INDOLE-2-CARBOXYLIC ACID ESTER DERIVATIVE | OTSUKA CHEM CO LTD | 1997-02-18 | — | — | JP | disclosed |