Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10093729 | 0.89 | GLA (0.46) | GLAGAAXDHCYP1A2KDM4E | |
| SCHEMBL8322220 | 0.87 | GLA (0.45) | GLAGAAXDHCYP1A2NR4A2 | |
| SCHEMBL8320971 | 0.87 | KDM4E (0.59) | GLAGAAXDHCYP1A2NR4A2 | |
| SCHEMBL8324052 | 0.87 | XDH (0.55) | GLAGAAXDHCYP1A2NR4A2 | |
| SCHEMBL19014158 | 0.87 | IDO1 (0.49) | GLAGAAXDHCYP1A2HRH4 | |
| SCHEMBL8320394 | 0.87 | GLA (0.45) | GLAGAAXDHCYP1A2NR4A2 | |
| SCHEMBL8319614 | 0.87 | GAA (0.62) | GLAGAAXDHCYP1A2KDM4E | |
| SCHEMBL8318535 | 0.87 | GLA (0.45) | GLAGAAXDHCYP1A2NR4A2 | |
| SCHEMBL8324172 | 0.86 | GLA (0.44) | GLAGAAXDHCYP1A2NR4A2 | |
| SCHEMBL8317583 | 0.85 | GLA (0.43) | GLAGAAXDHCYP1A2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101005761-B | Imazalil compositions comprising alkoxylated amines | JANSSEN PHARMACEUTICA NV | 2010-06-16 | — | — | CN | disclosed |
| US-7538127-B2 | Medicinal compounds | GLAXO GROUP LIMITED (GB) | 2009-05-26 | — | — | US | disclosed |
| US-20090105309-A1 | Medicinal Compounds | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | US | disclosed |
| US-7294650-B2 | Benzothiophen and thiochrone containing phenethanolamine derivatives for the treatment of respiratory disorders | GLAXO GROUP LIMITED (GB) | 2007-11-13 | — | — | US | disclosed |
| US-20070172385-A1 | Benzothiophen and thiochrone containing phenethanolamine derivatives for the treatment of respiratory disorders | GLAXO GROUP LIMITED (GB) | 2007-07-26 | — | — | US | disclosed |
| CN-101005761-A | Imazalil compositions comprising alkoxylated amines | JANSSEN PHARMACEUTICA NV (BE) | 2007-07-25 | — | — | CN | disclosed |
| US-20070135490-A1 | Phenetanolamine derivatives | GLAXO GROUP LIMITED (GB) | 2007-06-14 | — | — | US | disclosed |
| US-5866594-A | Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0791582-A1 | INDOLE-2-CARBOXYLIC ESTER DERIVATIVES AND AGRICULTURAL AND HORTICULTURAL BACTERIOCIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135490-A1 | Phenetanolamine derivatives | ADRB2, ADRB1, ADRB3 | GLA 2236/4885GAA 3063/4885XDH 651/4885 |
| US-20090105309-A1 | Medicinal Compounds | ADRB2, ADRB1, ADRB3 | GLA 1661/4885GAA 2239/4885XDH 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.