Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.44 |
| ▸ | OXTR | P30559 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316236 | 0.87 | AVPR2 (0.42) | AVPR2AVPR1AOXTR | |
| SCHEMBL7333364 | 0.86 | AVPR1A (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL8315532 | 0.86 | AVPR1A (0.55) | AVPR2AVPR1AOXTR | |
| SCHEMBL8314084 | 0.85 | AVPR1A (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL8317384 | 0.84 | AVPR1A (0.49) | AVPR2AVPR1AOXTRMEN1KMT2A | |
| SCHEMBL8318225 | 0.84 | AVPR1A (0.53) | AVPR2AVPR1AOXTR | |
| SCHEMBL8317702 | 0.84 | AVPR2 (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL8317401 | 0.82 | AVPR1A (0.50) | AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL8315606 | 0.82 | AVPR1A (0.47) | AVPR2AVPR1AOXTRMEN1KMT2A | |
| SCHEMBL8311577 | 0.82 | AVPR1A (0.51) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |