Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | DRD3 | P35462 | 7/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318672 | 1.00 | DPP4 (0.49) | DPP4DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8318673 | 1.00 | DPP4 (0.49) | DPP4DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL24672049 | 0.82 | FUCA1 (0.51) | DPP4DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL29960543 | 0.81 | DRD2 (0.60) | DPP4DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL350298 | 0.81 | DRD2 (0.60) | DPP4DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8314144 | 0.81 | DRD2 (0.60) | DPP4DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8314148 | 0.81 | DRD2 (0.60) | DPP4DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8313826 | 0.78 | DRD2 (0.67) | DPP4DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL8316979 | 0.78 | DRD2 (0.67) | DPP4DRD2DRD3S1PR1S1PR5 | |
| SCHEMBL1898802 | 0.77 | DPP4 (0.49) | DPP4DRD2DRD3S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691342-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-04-28 | — | — | EP | disclosed |
| US-5663191-A | PSYCHIATRIC DISEASES, ANXIETY AND ANTIDEPRESSANTS | ADIR ET COMPAGNIE (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0691342-A1 | Benzopyrane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |