Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322763 | 0.89 | LMNA (0.41) | LMNA | |
| SCHEMBL8317774 | 0.86 | MAPT (0.34) | ALDH1A1HSD17B10LMNAMAPTKDM4E | |
| SCHEMBL6140704 | 0.86 | MAPT (0.37) | ALDH1A1LMNAMAPTTP53MCL1 | |
| SCHEMBL6140175 | 0.86 | MAPT (0.37) | ALDH1A1LMNAMAPTTP53MCL1 | |
| SCHEMBL8643870 | 0.85 | KDM4E (0.31) | ALDH1A1HSD17B10LMNAMAPTKDM4E | |
| SCHEMBL279470 | 0.80 | LMNA (0.42) | ALDH1A1HSD17B10LMNAMAPTKDM4E | |
| SCHEMBL8317348 | 0.80 | ALDH1A1 (0.32) | ALDH1A1HSD17B10LMNAMAPTKDM4E | |
| SCHEMBL8319785 | 0.79 | — | — | |
| SCHEMBL3852488 | 0.78 | LMNA (0.52) | LMNATSHRTDP1 | |
| SCHEMBL279014 | 0.76 | LMNA (0.38) | LMNAMAPTMAOBMAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |