Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.53 |
| ▸ | BRD4 | O60885 | 7/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318012 | 0.94 | HDAC3 (0.52) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8317491 | 0.89 | HDAC3 (0.43) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8318456 | 0.89 | BRD4 (0.55) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8315794 | 0.89 | HDAC3 (0.48) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8319707 | 0.89 | HDAC3 (0.49) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8316577 | 0.89 | CCKBR (0.44) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8316213 | 0.88 | BRD4 (0.55) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8317832 | 0.88 | BRD4 (0.55) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8320494 | 0.87 | BRD4 (0.48) | CCKBRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8318236 | 0.86 | BRD4 (0.50) | CCKBRHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |