Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 4/20 | 0.39 |
| ▸ | EP300 | Q09472 | 3/20 | 0.39 |
| ▸ | BRD2 | P25440 | 3/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317338 | 0.90 | HDAC3 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8318973 | 0.89 | CCKBR (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8314769 | 0.89 | BRD4 (0.46) | BRD4BRD2BRD3 | |
| SCHEMBL8318636 | 0.86 | BRD4 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8321315 | 0.86 | BRD4 (0.39) | BRD4BRD2BRD3 | |
| SCHEMBL8316577 | 0.85 | CCKBR (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydrochloric Acid SCHEMBL8319535 | 0.85 | BRD4 (0.38) | BRD4BRD2BRD3 | |
| SCHEMBL8320433 | 0.84 | BRS3 (0.39) | BRD4BRD2BRD3 | |
| SCHEMBL8318012 | 0.83 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8321540 | 0.80 | BRD4 (0.43) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |