Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322219 | 0.84 | PTGER1 (0.52) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8323878 | 0.81 | PKM (0.51) | PTGER1PTGER4PTGER3PTGER2LMNA | |
| SCHEMBL8319879 | 0.81 | PTGER1 (0.58) | PTGER1PTGER4PTGER3PTGER2RAB9A | |
| SCHEMBL25340300 | 0.79 | SMN1; SMN2 (0.69) | NPC1RAB9ALMNACYP1A2CYP3A4 | |
| SCHEMBL8050948 | 0.78 | CYP19A1 (0.49) | PTGER1PTGER4PTGER3PTGER2RAB9A | |
| SCHEMBL9058140 | 0.78 | PTGER1 (0.73) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8522725 | 0.77 | PTGER1 (0.56) | PTGER1PTGER4PTGER3PTGER2LMNA | |
| Hydrochloric Acid SCHEMBL27619503 | 0.77 | CYP19A1 (0.48) | PTGER1PTGER4PTGER3PTGER2RAB9A | |
| SCHEMBL6261303 | 0.76 | LMNA (0.53) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8325118 | 0.76 | PTGER1 (0.60) | PTGER1PTGER4PTGER3PTGER2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |