Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471684 | 0.82 | NPSR1 (0.48) | KDM4ENPSR1ALDH1A1GAAHSD17B10 | |
| SCHEMBL8322828 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL11081953 | 0.79 | NPC1 (0.45) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL9202023 | 0.78 | NPSR1 (0.44) | KDM4ENPSR1ALDH1A1GAAHSD17B10 | |
| SCHEMBL17111836 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL22535980 | 0.75 | KDM4E (0.61) | KDM4ENPSR1ALDH1A1GAAHSD17B10 | |
| SCHEMBL4758833 | 0.75 | KDM4E (0.73) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL28000164 | 0.75 | ABL1 (0.50) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL18109486 | 0.75 | NPSR1 (0.44) | KDM4ENPSR1ALDH1A1HSD17B10HPGD | |
| SCHEMBL30608970 | 0.75 | NPSR1 (0.44) | KDM4ENPSR1ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959116-A | 5-NITRO PYRIDINE-2,3-DICARBOXYLIC ACID ESTER CHEMICAL INTERMEDIATES MADE BY REACTING THE N-OXIDES OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH NITRIC ACID OR SODIUM NITRATE, THEN REMOVING THE N-OXIDE GROUP | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | claimed |
| EP-0663399-B1 | Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants | BASF AG (DE) | 1998-06-10 | — | — | EP | claimed |
| US-5959116-A | 5-NITRO PYRIDINE-2,3-DICARBOXYLIC ACID ESTER CHEMICAL INTERMEDIATES MADE BY REACTING THE N-OXIDES OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH NITRIC ACID OR SODIUM NITRATE, THEN REMOVING THE N-OXIDE GROUP | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5571774-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |