Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318983 | 0.87 | ALDH1A1 (0.50) | KDM4EALDH1A1HSD17B10CYP1A2TSHR | |
| SCHEMBL13285824 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL9800425 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10CYP1A2TSHR | |
| SCHEMBL8661094 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1HSD17B10CYP1A2TSHR | |
| SCHEMBL9315414 | 0.81 | SMN1; SMN2 (0.56) | KDM4EALDH1A1HSD17B10CYP1A2TSHR | |
| SCHEMBL8319338 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10TSHRGAA | |
| SCHEMBL9205477 | 0.79 | TSHR (0.49) | KDM4EALDH1A1HSD17B10CYP1A2TSHR | |
| SCHEMBL27140789 | 0.79 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL31607744 | 0.79 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL7471868 | 0.79 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959116-A | 5-NITRO PYRIDINE-2,3-DICARBOXYLIC ACID ESTER CHEMICAL INTERMEDIATES MADE BY REACTING THE N-OXIDES OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH NITRIC ACID OR SODIUM NITRATE, THEN REMOVING THE N-OXIDE GROUP | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5840904-A | Fluoro-pyridine-2,3-dicarboxylic anhydrides which are intermediates for herbicidal pyridine-2,3-dicarboximides | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| US-5679622-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5571774-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |