Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.47 |
| ▸ | BRD2 | P25440 | 11/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 11/20 | 0.46 |
| ▸ | OXTR | P30559 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318824 | 0.94 | BRD4 (0.45) | BRD4BRD2BRD3OXTRGLA | |
| SCHEMBL8320603 | 0.93 | BRD4 (0.48) | BRD4BRD2BRD3GLA | |
| SCHEMBL8317515 | 0.92 | BRD4 (0.43) | BRD4BRD2BRD3OXTRGLA | |
| SCHEMBL8322984 | 0.91 | BRD4 (0.51) | BRD4BRD2BRD3NPC1RAB9A | |
| SCHEMBL8318078 | 0.90 | BRD4 (0.44) | BRD4BRD2BRD3OXTRCYP11B1 | |
| SCHEMBL8318050 | 0.89 | BRD4 (0.63) | BRD4BRD2BRD3GLA | |
| SCHEMBL8316213 | 0.86 | BRD4 (0.55) | BRD4BRD2BRD3 | |
| SCHEMBL8318331 | 0.86 | BRD4 (0.49) | BRD4BRD2BRD3GAA | |
| SCHEMBL8316386 | 0.85 | BRD4 (0.44) | BRD4BRD2BRD3NPC1RAB9A | |
| SCHEMBL8318456 | 0.84 | BRD4 (0.55) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | claimed |
| US-5807850-A | Therapeutic agent for osteoporosis and triazepine compound | JAPAN TOBACCO, INC. (JP) | 1998-09-15 | — | — | US | claimed |
| EP-0792880-A1 | OSTEOPOROSIS REMEDY AND TRIAZEPINE COMPOUND | Japan Tobacco Inc. (JP) | 1997-09-03 | — | — | EP | claimed |
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5807850-A | Therapeutic agent for osteoporosis and triazepine compound | JAPAN TOBACCO, INC. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0792880-A1 | OSTEOPOROSIS REMEDY AND TRIAZEPINE COMPOUND | Japan Tobacco Inc. (JP) | 1997-09-03 | — | — | EP | disclosed |