Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.31 |
| ▸ | CLK1 | P49759 | 3/20 | 0.31 |
| ▸ | CLK3 | P49761 | 3/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.31 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.31 |
| ▸ | MAP3K19 | Q56UN5 | 2/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.31 |
| ▸ | CSNK1G3 | Q9Y6M4 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319481 | 0.86 | HDAC6 (0.42) | HDAC6MAPTL3MBTL1 | |
| SCHEMBL8319484 | 0.86 | HDAC6 (0.42) | HDAC6MAPTL3MBTL1 | |
| SCHEMBL6747666 | 0.84 | KDM4E (0.40) | HDAC6HSD17B10ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6747555 | 0.82 | HDAC6 (0.44) | HDAC6MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL6752015 | 0.81 | HDAC6 (0.37) | HDAC6MAPTHSD17B10CSNK1ECLK1 | |
| SCHEMBL6752012 | 0.81 | HDAC6 (0.37) | HDAC6MAPTHSD17B10CSNK1ECLK1 | |
| SCHEMBL6747171 | 0.81 | PABPC1 (0.41) | HDAC6ALDH1A1SMN1; SMN2LMNAAPOBEC3A | |
| SCHEMBL6749131 | 0.81 | MAPT (0.39) | HDAC6MAPTHSD17B10DYRK1AALDH1A1 | |
| SCHEMBL6749127 | 0.81 | MAPT (0.39) | HDAC6MAPTHSD17B10DYRK1AALDH1A1 | |
| SCHEMBL6749215 | 0.80 | HDAC6 (0.34) | HDAC6ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | HDAC6 1953/4885MAPT 1257/4885HSD17B10 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.