Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 18/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14380783 | 0.89 | ACE (0.81) | ACEABCB11PDE3ALMNA | |
| SCHEMBL13940747 | 0.89 | ACE (0.81) | ACEABCB11PDE3ALMNA | |
| SCHEMBL8325515 | 0.89 | ACE (0.67) | ACEABCB11PDE3ALMNA | |
| SCHEMBL8328018 | 0.89 | ACE (0.86) | ACEABCB11PDE3A | |
| SCHEMBL14545637 | 0.88 | ACE (0.64) | ACEABCB11PDE3ALMNA | |
| SCHEMBL8324111 | 0.82 | ACE (0.58) | ACEABCB11LMNA | |
| Quinaprilat SCHEMBL11306348 | 0.81 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL9253792 | 0.81 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL113237 | 0.81 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL11286571 | 0.81 | ACE (1.00) | ACEABCB11PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004054980-A1 | CRYSTALLINE FORM OF QUINAPRIL HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | LUPIN LIMITED (IN) | 2004-07-01 | — | — | WO | disclosed |