Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.82 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinaprilat SCHEMBL7392611 | 1.00 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL11306348 | 1.00 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL29598971 | 1.00 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL11286565 | 1.00 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL11286571 | 1.00 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL7421419 | 1.00 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL113237 | 1.00 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL6438000 | 1.00 | ACE (1.00) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL27697059 | 0.99 | ACE (0.98) | ACEABCB11PDE3A | |
| Quinaprilat SCHEMBL27717008 | 0.99 | ACE (0.98) | ACEABCB11PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4217994-A | — | — | None | — | — | JP | disclosed |
| US-5401766-A | Hypotensive agents with vasodilation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| EP-0328160-B1 | Amino acid derivatives, process to prepare them, composition containing them and their use | HOECHST AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| US-5162362-A | Hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5158959-A | Treatment of hypertension | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |
| JP-H04217994-A | AMINO ACID DERIVATIVE AND PREPARATION THEREOF | HOECHST AG | 1992-08-07 | — | — | JP | disclosed |
| EP-0046953-B1 | AMINO ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-12-06 | — | — | EP | disclosed |
| EP-0328160-A1 | Amino acid derivatives, process to prepare them, composition containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | disclosed |
| EP-0065301-A1 | Isoquinoline carboxylic acid derivates, process for preparing and pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-11-24 | — | — | EP | disclosed |
| EP-0046953-A2 | Amino acid derivatives, processes for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-10 | — | — | EP | disclosed |