Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14545775 | 0.89 | KMT2A (0.54) | ACEHDAC8ABCB11KMT2AMEN1 | |
| SCHEMBL13173445 | 0.88 | ACE (0.69) | ACEABCB11KMT2AMEN1LMNA | |
| SCHEMBL16624673 | 0.85 | ACE (0.56) | ACEABCB11KMT2AMEN1LMNA | |
| SCHEMBL8319633 | 0.82 | ACE (0.68) | ACEABCB11LMNA | |
| SCHEMBL8325515 | 0.81 | ACE (0.67) | ACEABCB11LMNA | |
| SCHEMBL8328018 | 0.81 | ACE (0.86) | ACEABCB11 | |
| SCHEMBL4952073 | 0.77 | HDAC8 (0.74) | ACEHDAC8KMT2AMEN1KDM4E | |
| SCHEMBL9545302 | 0.77 | KMT2A (0.55) | HDAC8KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL8320933 | 0.76 | MME (0.51) | ACEKMT2AMEN1ALDH1A1 | |
| SCHEMBL20227445 | 0.76 | ACE (0.67) | ACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572661-B1 | CRYSTALLINE FORM OF QUINAPRIL HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | LUPIN LTD (IN) | 2007-04-25 | — | — | EP | disclosed |
| WO-2004054980-A1 | CRYSTALLINE FORM OF QUINAPRIL HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME | LUPIN LIMITED (IN) | 2004-07-01 | — | — | WO | disclosed |