Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330367 | 0.87 | KCNH2 (0.45) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| SCHEMBL8323756 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8326210 | 0.85 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8323392 | 0.84 | KCNH2 (0.51) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8323758 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8323314 | 0.81 | PIK3CG (0.44) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8922878 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL9152004 | 0.78 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9151237 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8323542 | 0.76 | DRD3 (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| US-5679689-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |